Researcher in Myeloid Cancer

**About the position**:
At the Stem Cells, Ageing and Cancer team, Centre of Excellence CRESCO and Section for Microbiology, Oslo University Hospital, lead by Lorena Arranz, we have a full-time temporary position for three years as a researcher.
- “NEUROTARGET” aims to dissect how newly identified genetic variants involved in the sympathetic nervous system function are enriched in patients with myeloid cancers, their impact on hematopoiesis, and their potential as targets for therapeutic strategies. A central objective is the development of relevant mouse models, to characterize the pathogenic potential of the variants in vivo and the value of their targeting as therapy in preclinical models. Another important objective involves research with human stem cells and relevant stem cell niche components ex vivo and in vivo. The aim of NEUROTARGET is to provide the scope for a larger project with expected benefit for future care of patients with myeloid cancers.
**Key information**:
- Application deadline:
-
- Employer:
- Oslo universitetssykehus HF
- Town/city:
- Oslo
- Title:
- Researcher
- Positions:
- 1
- Full-time/part-time:
- Full-time
- Employment type:
- Contract
- Percentage of full-time:
- 100
- Webcruiter ID:
-
- Start date:
-
- End date:
-
- Social sharing:
- Share on x
**Key responsibilites**:
- Mouse colony management.
- In vivo experiments, including in vivo hematopoietic stem cell transplantation models with mouse and human cells, follow-up and endpoint analysis by flow cytometry, CFU-C, immunofluorescence, etc.
- Application to ethical approvals and reporting of animal use in experiments.
- Handling of patient material and biobanking. Sometimes we receive samples from patients, which are not always possible to agree in advance. Therefore, sometimes the working hours require certain adaptability.
- Setting up and optimizing new methods relevant to the project.
- Communication of results in congresses and other scientific meetings.
- Writing of reports, abstracts, protocols, papers, etc.
**Qualifications**:
- PhD in physiopathology or cancer biology.
- Extensive documented experience with animal models in the field of hematology and active FELASA C certification are required.
- Strong documented interest in myeloid cancer biology and translational research, with at least two high-quality publications as first author in the field.
- Documented experience with stem cell transplants in mice is required.
- Strong expertise in conventional and spectral flow cytometry method development and data analysis, using BD Fortessa analyzer and Aria sorter, SONY ID7000 analyzer and CYTEK Aurora analyzer is required.
- Experience in molecular biology with low input (eg. multiplex cytokine assays, ddPCR, etc) is required.
- Experience with confocal microscopy is an advantage.
- Strong written and verbal communication skills in English.
**Personal skills**:
We are looking for someone:
- Precise and structured.
- With good collaboration skills and ability to train others.
- Motivated and hardworking.
- That contributes to a good working environment.
- That shares our research vision.
- That has flexibility to adapt to different working hours when needed.
- With immediate availability.
**We offer**:
- A highly collaborative and interdisciplinary research environment.
- Access to state-of-the-art technology with a move to Oslo Life Science Building in 2027.
- Opportunities to work on biologically and clinically impactful questions.
- Strong support for scientific development and career progression.
- Good working environment at the professional and social levels.
- Competitive salary according to qualifications.
**Address**: Forskningsveien 1, 0373 Oslo, Norway**:
**Open directions**(in new tab)**
**Contacts**:
**Hilde Loge Nilsen**
- Head of Section
- Phone:
**About the employer**:
Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.