Medical Director

GRANITE BIO is a private biotechnology company located in Basel (Switzerland). GRANITE BIO is supported by top-tier investors with ~$100M raised to date. Based on fundamental research conducted over the last two decades, GRANITE BIO’s is pursuing a differentiated approach to transform inflammatory, autoimmune, and fibrotic conditions. Both our programs are first-in-class monoclonal antibodies for large market opportunities in Immunology and Inflammation. GRT-001, the lead asset, depletes inflammatory monocytes. It has just completed a Phase 1a trial in healthy volunteers and has shown favorable safety and pharmacodynamic effect. The Phase 1b trial in patients with Ulcerative Colitis has just started. GRT-002 is an IL-3 neutralizing antibody that is thought to play an important role in type II inflammation. Our company fosters an open, inter-disciplinary, diverse, international and creative working environment. We enable work-from-home options according to our internal workflows. The successful candidate will be highly motivated and enthusiastic with a positive “can do” attitude, attention to details and innovation, strong organizational and communication skills.ResponsibilitiesDesign, execution/conduct and report of Ph1/2 clinical trials in I&I spaceContribute to medical team and clinical development strategyProvide guidance and expertise in the development of clinical trial protocols and further study relevant documents, such as ICF, IB, SoA, TPP, SAP etcEnsure that safety and efficacy data is generated and analyzed according to GCP/SOPs, corporate strategy and timelinesPerform medical monitoring activities (such as medical oversight of the study, answer questions about eligibility, review safety and adverse event data, medical oversight of coding activities)Work closely with cross-functional team members to ensure planning and execution of clinical trials to meet key study milestonesPlay a key role in the development of statistical analysis plan, and in the review, interpretation, and communication of clinical trial data from clinical trialsAuthor and develop clinical documents like, clinical study protocols and amendments and review other clinical documents like safety management plan, medical monitoring planWork closely with colleagues from Clinical Operations and Clinical Biomarker department to deliver clinical study program goals and milestonesQualificationsAdvanced medical degree (MD or equivalent)At least 3 years of experience in clinical research or clinical development within the pharmaceutical or biotechnology industry, ideally with exposure to early clinical trialsStrong ability to build collaborative working relationships with physicians, expert consultants, and external vendorsStrong analytical mindset with excellent written and verbal communication skillsExceptional attention to detail, sound judgement, and strong organisational skillsSolid knowledge of clinical trial methodology as well as regulatory and compliance requirements for clinical trialsGood understanding of Good Clinical Practice (GCP), Good Laboratory Practice (GLP), and clinical study designUnderstanding of the framework and complexities of early multi‑centre clinical trials, including working with CROs and CDOsIdeally, experience in autoimmune disease and/or the IBD / inflammation and immunology (I&I) spaceEffective communicator who shares information transparently and strategicallyTeam player with strong listening skillsComfortable working in a dynamic, fit‑for‑purpose biotech environmentAble to thrive in collaborative and sometimes ambiguous settings, with a proactive and solution-oriented mindsetStrong planning, organisational, and problem‑solving skills, with the ability to support efficient operational execution of clinical programmes, studies, and related projectsEnjoys contributing to diverse teams, whether in a leading role or as an active team memberTalented, proactive, and passionate medical professional inspired by the opportunity to bring innovation to patients with unmet medical needsWhat we currently offerPrime LocationCommuter BenefitsFlexible WorkingAdditional Time OffIn addition to 24 days of annual leave, our offices and labs are closed between Christmas and New Year.Your Birthday OffCoffee & ConnectionPersonal DevelopmentCreative EnvironmentDiverse TeamTeam EventsPlease note that these benefits are subject to change at the company’s discretion and do not constitute a contractual entitlement. #J-18808-Ljbffr